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Is Your Metabolism to Blame?  
By Ahmed H. Kissebah, M.D., Ph.D.
 

The term “metabolism” is a word commonly used by almost every source that deals with weight loss, obesity research, and weight management. We also receive a lot of inquiries from TOPS members about the actual meaning of this word. There are conflicting notions about whether our metabolism is to blame or not in our struggle to reduce our weight and then to maintain the goal weight. How can we understand and determine its impact on weight gain and—at least, in some individuals—its effects on maintaining our weight goal? This article will address this issue.

What is metabolism?
If we compared your body to a car, metabolism is everything that happens in the engine when it is running. Human metabolism is a set of biochemical events that keeps us alive. Your metabolic rate is the rate at which the body uses energy—expressed as calories burned—over a given time. It includes three categories:

1. Calories needed for basic body functions such as breathing, pumping of the heart, maintaining body temperature, etc., is known as the Basal Metabolic Rate (BMR). It accounts for usually 50% to 60% of the calories expended per day.

2. Calories needed for the processes of eating, digestion, absorption and maintaining body nutrients is known as the Thermic Effect of Eating (TEE). It utilizes between 10% and 15% of the calories expended per day.

3. Calories used for physical activities, called Activity Related Energy (ARE), account for the rest of the calories burned per day.

Thus, the metabolic rate is adjusted to process what one eats, to provide the power to move around and exercise, and to maintain the energy required for basic bodily functions.

 Factors Affecting the Metabolic Rate
What people need to know is how to boost the metabolic rate so that a person can burn more calories and, consequently, control the process of weight gain. First, BMR depends on age, gender, and body size and composition, as well as the hormonal balance. Women generally tend to have a lower BMR than men, and older people tend to have a lower BMR than younger people. This is because the major burning organs in the body are the muscles that, on a per unit basis, burn more calories than the relatively fatty organs and, thus, help to boost the BMR. The metabolic rate is also affected by climate. It is increased in hot climates and sometimes also with the cold. It is increased by fever and decreased by fasting. It is also affected by our genes. Thus, in order to increase the calorie expenditure by increasing BMR, one has to emphasize a build-up of the muscle mass.

This can occur with the various forms of resistance exercise and weight training. Choosing the type of exercise is an important issue for the obese individual. Pushing against the walls or floor, lifting weights, or stretch exercises are all very helpful in building up the muscle mass in the upper body. The best exercise for the lower body is leisurely walking, which is also recommended for people to control their weight after reaching goal.

One important thing to remember is that repeated bouts of weight loss and regain, which is common among obese individuals, can very seriously affect the muscle mass. Every time a person loses weight, the major component lost—at least in the beginning—is muscle. When this person regains weight, what is regained is primarily fat and not muscle. Repeated bouts of this behavior could eventually change the composition of the body by decreasing the overall muscle mass and increasing the fat mass and, thereby, reducing the BMR. Surprisingly, unconscious fidgeting or moving around a lot is one of the best means to having a higher metabolic rate. It takes calories to fidget, so you may want to become a fidgiter.

Basal Metabolic Rate throughout Life and the Effects of Hormones
Boys and girls, when examined at age 5, have the same body composition, and the relative fat to muscle mass is the same for both sexes. At puberty, girls have an increase in the relative fat to muscle mass by about 10% to 15%. Whereas, boys will maintain a lower fat percentage, they also show an increase in their relative muscle mass. This sex difference remains throughout adulthood, but is made worse by pregnancy in women and when men experience middle-age crisis. In both cases, the ratio of fat to muscle will tend to increase. Men will also gain the majority of their fat in the central part of the body. This type of fat is highly active and has serious adversities to health. Women, on the other hand, tend to deposit the majority of their gained fat in the thighs and hips. Though this fat is mechanically harmful and may not be accepted emotionally, it has a lesser impact on one’s health.

These differences throughout these phases are engineered by the hormonal differences between men and women. After age 40, there is a gradual decline in the sex hormones in both men and women. This results in a gradual decrease in the muscle mass and an increase in the relative fat mass, which is paralleled by a gradual drop in the BMR. The total body energy expenditure in general falls by about 10% to 15% between ages 40 to 70. This means that the energy requirements with aging become less and the goal of maintaining weight requires a gradual reduction in caloric intake. Hormonal replacement therapy as well as certain diseases will also affect the circulating hormonal levels.

Is Your Metabolism to Blame?
Many people blame their obesity on having a low BMR, but this is not all true. Although a low BMR might make one predisposed to weight gain, the BMR is usually higher in the obese and overweight people because they need more calories to deal with their higher body weights.

We all know that individuals who have lost weight to goal and become KOPS have to consume fewer calories than another person of the same weight  who has never gained or lost weight. Thus, it is easier for a KOPS to gain the weight back unless they keep consuming fewer calories all their life. That is because when they lost the weight, they not only lost the fat but also a great deal of their muscle mass. Their body composition is essentially the same as an obese person, except they are thinner. That person will require the gain of muscle mass by doing those resistance exercises as described earlier.

Although promoters of certain diets would say that consuming exclusively protein-rich diets could boost your metabolic rate and weight loss, this is not true. The process of weight loss and maintenance is only determined by how many calories the person eats and how many calories are being expended. It is true that it takes the body a little more energy to process proteins than other nutrients. However, eating more protein has only a very small effect on the BMR. Other factors that are expected to increase metabolic rate are eating frequent, small meals; consuming green tea supplements; and getting enough sleep. Green tea extract is often promoted as a weight-loss aid and might, in theory, help. It contains certain “vital chemicals,” including caffeine, that can briefly increase BMR, although the increase is small. Inadequate sleep has also been linked with weight gain and, possibly, reduced BMR.

Although it is not easy or even possible to boost the BMR, it is much easier to increase the activity-related energy expenditure simply by exercising more. The calories one can burn during a workout can be highly important in losing weight and maintaining that weight loss. Aerobic exercise such as running, biking, swimming or brisk walking can help to burn a significant portion of the daily calories expended. Thus, there should be a balance between the time spent in resistance training (which affects the body’s muscle mass and BMR) and aerobic exercise (that helps to boost the calories spent by physical activities). A balanced workout should include both activities. However, one has to be realistic and consider the fact that many overweight individuals have joint and tendon problems, back issues and even heart disease. The activities selected for these individuals have to take into account their physical limitations. These individuals should consult with their personal physician and also with a specialist in exercise training.

Therefore, is the metabolic rate to blame? The evidence does not support this claim. It is up to the individual to adopt a lifestyle behavior to positively affect the body’s composition and, consequently, the BMR as well as their activity level, which also impacts their caloric expenditure.

Who Should We Blame?
First and foremost, are your genes. The metabolic rate like most body functions is under the control of our inherited network of genes. There are those individuals who can consume a larger number of calories than you, yet remain slim throughout life. Their metabolic rate is set at a higher level. Other people eat much lesser amounts of food and yet can easily gain weight. This is an area of research that hopefully will disclose soon some means to readjust these differences.

Second, one should be aware of the various factors that affect the body’s metabolism throughout her/his life and utilize this knowledge to offset the unwanted effects of pregnancy in women, middle-age crisis in men, and aging in both. One can always, however, increase their metabolic rate by adopting lifestyle behaviors that serve to maintain the muscle mass and the body’s composition at a favorable state. This will sustain a higher basal and activity related metabolic rate. As a TOPS member, these tools are already in your hands. You can do it!

 

Dr. Ahmed Kissebah, M.D., Ph.D., is professor of medicine and pharmacology and director of the General Clinical Research Center, Medical College of Wisconsin. Dr. Kissebah directs the TOPS-funded research there and serves as TOPS’ medical advisor. He also answers the questions featured in the “Medical Q&A” column of TOPS News.

 
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